Amyloidosis Lichen - Symptoms & Treatment

Amyloidosis lichen is a rare and potentially fatal disease that occurs when substances called amyloid proteins build up in your body's organs. Amyloidosis can occur as its own entity or "secondarily" as a result of another illness, including multiple myeloma, chronic infections (such as tuberculosis or osteomyelitis), or chronic inflammatory diseases (such as rheumatoid arthritis and ankylosing spondylitis ). The symptoms depend on the organs affected by the deposits, which can include the tongue, intestines, skeletal and smooth muscles, nerves, skin, ligaments, heart, liver, spleen, and kidneys. Many forms of amyloidosis exist, and the disease can be classified into four groups: primary amyloidosis, secondary amyloidosis, hereditary amyloidosis, and amyloidosis associated with normal aging. In still other cases, amyloidosis may occur as a result of kidney disease in people who have undergone long-term dialysis therapy. The severity of the disease depends on which organs are affected by amyloid deposits. Amyloidosis is twice as common in men as in women and is more common among older people.

Amyloidosis lichen sometimes develops when a person has certain forms of cancer, such as multiple myeloma, Hodgkin's disease or familial Mediterranean fever (an intestinal disorder). Systemic amyloidosis can be serious or even life-threatening, depending on which parts of the body are affected. Amyloidosis can affect different organs in different people, and there are many types of amyloid. This form of amyloidosis is called localized amyloidosis. Amyloidosis that affects tissues throughout the body is referred to as systemic amyloidosis. Amyloidosis lichen affects more than 90% of people with Type II diabetes mellitus, people with certain cancers of the thyroid or other tumors of the endocrine system, and about 80% of people over age 80. Primary amyloidosis the most common type of amyloidosis in the United States, with estimates of up to 2000 cases diagnosed each year, and occasionally occurs with multiple myeloma. Older discussions of amyloidosis refer often to primary amyloidosis or to myeloma-associated amyloidosis, the fibril protein of each of which is an immunoglobulin light chain peptide or fragment.

Causes of Amyloidosis lichen

The common causes and risk factor's of Amyloidosis lichen include the following:

• The exect cause of amyloidosis lichen is unknown.
• The condition is related to abnormal production of immunoglobulins by a type of immune cell called plasma cells.
• You may be at increased risk if you have a chronic infectious or inflammatory disease.
• Family history of Amyloidosis lichen.
• If you have kidney disease requiring kidney dialysis - particularly for longer than five years - you may be at increased risk of amyloidosis lichen.

Symptoms of Amyloidosis lichen

Some symptoms related to Amyloidosis lichen are as follows:

• Fatigue.
• An enlarged tongue (macroglossia).
• Weak hand grip.
• Difficulty breathing.
• Swelling of your ankles and legs.
• Weight loss.
• Numbness or tingling in your hands or feet.
• Diarrhea.
• Skin changes.
• Hoarseness or changing voice.

Treatment of Amyloidosis lichen

Here is list of the methods for treating Amyloidosis lichen:

• There is no cure for most cases of amyloidosis lichen.
• Some medications, such as corticosteroids, chemotherapy agents and colchicine, may decrease inflammation and treat some cases of amyloidosis lichen, but they are not very effective if the disease is severe or highly advanced.
• Peripheral blood stem cell transplantation involves using high-dose chemotherapy and transfusion of previously collected immature blood cells (stem cells) to replace diseased or damaged marrow.
• Attacks of fever, joint, and abdominal pains, can be prevented with the medication colchicine.

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