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Ebola Virus Infection - Symptoms & Treatment
Zaire ebolavirus causes severe hemorrhagic fever in humans with up to 90% case-fatality rates. Guinea pig and mouse models it was possible to protect 50% and 100% of the animals, respectively, following treatment as late as 24 h after lethal challenge. Eight rhesus macaques were protected if treated 20 to 30 min following an otherwise uniformly lethal infection. Ebola infections and is particularly suited for use in accidentally exposed individuals and in the control of secondary tranEbola viruses are highly lethal human pathogens that have received considerable attention in recent years due to an increasing re-emergence in Central Africa and a potential for use as a biological weapon. Ebola virus infections has been much slower and there is clearly an urgent need to develop effective post-exposure strategies to respond to future outbreaks and acts of bioterrorism. Ebola virus glycoprotein completely protected rodents and nonhuman primates from lethal Ebola challenge. Ebola infections and is particularly suited for use in accidentally exposed individuals and in the control of secondary transmission during naturally occurring outbreaks or deliberate release. smission during naturally occurring outbreaks or deliberate release.
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